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1

Discovery of Methyl 4′-Methyl-5-(7-nitrobenzo[ c ][1,2,5]oxadiazol-4-yl)-[1,1′-biphenyl]-3-carboxylate, an Improved Small-Molecule Inhibitor of c-Myc-Max Dimerization

Chauhan, Jay, Wang, Huabo, Yap, Jeremy L., Sabato, Philip E., Hu, Angela, Prochownik, Edward V., Fletcher, Steven

Journal:

Year:

2014

Language:

english

File:

PDF, 1.03 MB

english, 2014

2

miR-148a inhibits colitis and colitis-associated tumorigenesis in mice

Zhu, Yahui, Gu, Li, Li, Yajun, Lin, Xi, Shen, Hongxing, Cui, Kaisa, Chen, Li, Zhou, Feng, Zhao, Qiu, Zhang, Jinxiang, Zhong, Bo, Prochownik, Edward, Li, Youjun

Journal:

Cell Death & Differentiation

Year:

2017

Language:

english

File:

PDF, 4.81 MB

english, 2017

3

Dynamic in vivo interactions among Myc network members

Yin, Xiao-ying, Landay, Melanie F, Han, Weiping, Levitan, Edwin S, Watkins, Simon C, Levenson, Richard M, Farkas, Daniel L, Prochownik, Edward V

Journal:

Year:

2001

Language:

english

File:

PDF, 922 KB

english, 2001

4

Assignment of the Human MAD and MXI1 Genes to Chromosomes 2p12-p13 and 10q24-q25

David N. Shapiro, Virginia Valentine, Linette Eagle, Xiaoying Yin, Stephan W. Morris, Edward V. Prochownik

Journal:

Year:

1994

File:

PDF, 255 KB

1994

5

Molecular genetics of inherited antithrombin III deficiencies

Edward V. Prochownik

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 390 KB

english, 1989

6

Embryonal rhabdomyosarcoma of the ampulla of vater with long-term survival following pancreaticoduodenectomy

Michael G. Caty, Keith T. Oldham, Edward V. Prochownik

Journal:

Journal of Pediatric Surgery

Year:

1990

Language:

english

File:

PDF, 1.32 MB

english, 1990

7

c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.:

Edmunds, Lia R., Sharma, Lokendra, Kang, Audry, Lu, Jie, Vockley, Jerry, Basu, Shrabani, Uppala, Radha, Goetzman, Eric S., Beck, Megan E., Scott, Donald, Prochownik, Edward V.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 610 KB

english, 2015

8

A Point Mutation in the MyoD Basic Domain Imparts c-Myc-Like Properties

Mary E. Van Antwerp, De Gao Chen, Christina Chang and Edward V. Prochownik

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.20 MB

english, 1992

9

Sequential Adaptive Changes in a c-Myc-Driven Model of Hepatocellular Carcinoma

Dolezal, James M., Wang, Huabo, Kulkarni, Sucheta, Jackson, Laura, Lu, Jie, Ranganathan, Sarangarajan, Goetzman, Eric S., Bharathi, Sivakama, Beezhold, Kevin, Byersdorfer, Craig A., Prochownik, Edward

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

10

Genetic dissection of c-myc apoptotic pathways

Nesbit, Chadd E, Tersak, Jean M, Grove, Linette E, Drzal, Amy, Choi, Hyunjung, Prochownik, Edward V

Journal:

Year:

2000

Language:

english

File:

PDF, 679 KB

english, 2000

11

Changes in protein kinase C activity are associated with the differentiation of Friend erythroleukemia cells

Kenneth J. Balazovich, Douglas Portnow, Laurence A. Boxer, Edward V. Prochownik

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1987

Language:

english

File:

PDF, 696 KB

english, 1987

12

Mechanism of Small-Molecule Binding by Intrinsically Disordered Proteins

Metallo, Steven J., Follis, Ariele Viacava, Hammoudeh, Dalia I., Prochownik, Edward V.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

13

c-Myc Is Required for the ChREBP-Dependent Activation of Glucose-Responsive Genes

Zhang, Pili, Metukuri, Mallikarjurna R., Bindom, Sharell M., Prochownik, Edward V., O'Doherty, Robert M., Scott, Donald K.

Journal:

Molecular Endocrinology

Year:

2010

Language:

english

File:

PDF, 647 KB

english, 2010

14

Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers

Dolezal, James M., Dash, Arie P., Prochownik, Edward V.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.66 MB

english, 2018

15

Nucleic acid sequences of primate type C viruses in normal and neoplastic human tissues

PROCHOWNIK, EDWARD V., KIRSTEN, WERNER H.

Journal:

Year:

1977

File:

PDF, 345 KB

1977

16

Small-molecule inhibitors of the Myc oncoprotein

Fletcher, Steven, Prochownik, Edward V.

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

17

Mmip-2/Rnf-17 enhances c-Myc function and regulates some target genes in common with glucocorticoid hormones

Yin, Xiao-Ying, Grove, Linnette E, Prochownik, Edward V

Journal:

Year:

2001

Language:

english

File:

PDF, 329 KB

english, 2001

18

Amplification of glyceronephosphate O-acyltransferase and recruitment of USP30 stabilize DRP1 to promote hepatocarcinogenesis

Gu, Li, Zhu, Yahui, Lin, Xi, Li, Yajun, Cui, Kaisa, Prochownik, Edward V, Li, Youjun

Journal:

Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.83 MB

english, 2018

19

Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis

Zhu, Yahui, Gu, Li, Lin, Xi, Liu, Cheng, Lu, Bingjun, Cui, Kaisa, Zhou, Feng, Zhao, Qiu, Prochownik, Edward V., Fan, Chengpeng, Li, Youjun

Journal:

Year:

2019

Language:

english

File:

PDF, 4.55 MB

english, 2019

20

Myc and ChREBP Transcription Factors Cooperatively Regulate Normal and Neoplastic Hepatocyte Proliferation in Mice

Wang, Huabo, Dolezal, James M., Kulkarni, Sucheta, Lu, Jie, Mandel, Jordan, Jackson, Laura E., Alencastro, Frances, Duncan, Andrew W., Prochownik, Edward V.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 3.00 MB

english, 2018

21

Establishment of an apoptosis-resistant and growth-controllable cell line by transfecting with inducible antisense c-Jun gene

Yon Hui Kim, Takehiro Iida, Tetsuo Fujita, Satoshi Terada, Atsushi Kitayama, Hiroshi Ueda, Edward V. Prochownik, Eiji Suzuki

Journal:

Biotechnology and Bioengineering

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

22

c-Myc: Linking Transformation and Genomic Instability

Prochownik, Edward

Journal:

Current Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

23

Structural Rationale for the Coupled Binding and Unfolding of the c-Myc Oncoprotein by Small Molecules

Ariele Viacava Follis, Dalia I. Hammoudeh, Huabo Wang, Edward V. Prochownik, Steven J. Metallo

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 511 KB

english, 2008

24

Discovery of Novel Myc−Max Heterodimer Disruptors with a Three-Dimensional Pharmacophore Model

Mustata, Gabriela, Follis, Ariele Viacava, Hammoudeh, Dalia I., Metallo, Steven J., Wang, Huabo, Prochownik, Edward V., Lazo, John S., Bahar, Ivet

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 375 KB

english, 2009

25

Biology of Marrow Stromal Cell Lines Derived from Long-Term Bone Marrow Cultures of Trp53-Deficient Mice

Michael W. Epperly, Jenifer A. Bray, Timothy M. Carlos, Edward Prochownik and Joel S. Greenberger

Journal:

Radiation Research

Year:

1999

Language:

english

File:

PDF, 1.82 MB

english, 1999

26

SIRT5 Binds to Cardiolipin and Regulates the Electron Transport Chain

Zhang, Yuxun, Bharathi, Sivakama S, Rardin, Matthew J, Lu, Jie, Maringer, Katherine V, Sims-Lucas, Sunder, Prochownik, Edward V, Gibson, Bradford W, Goetzman, Eric S

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 897 KB

english, 2017

27

Sequential analysis of transcript expression patterns improves survival prediction in multiple cancers

Mandel, Jordan, Avula, Raghunandan, Prochownik, Edward V.

Journal:

Year:

2020

File:

PDF, 7.21 MB

2020

28

Inhibition of reverse transcriptases of primate type C viruses by 7S immunoglobulin from patients with leukaemia

PROCHOWNIK, EDWARD V., KIRSTEN, WERNER H.

Journal:

Year:

1976

File:

PDF, 444 KB

1976

29

Low molecular weight inhibitors of Myc–Max interaction and function

Yin, Xiaoying, Giap, Christine, Lazo, John S, Prochownik, Edward V

Journal:

Year:

2003

Language:

english

File:

PDF, 341 KB

english, 2003

30

The Ever Expanding Role for c-Myc in Promoting Genomic Instability

Prochownik, Edward V., Li, Youjun

Journal:

Year:

2007

Language:

english

File:

PDF, 464 KB

english, 2007

31

Mmip-2, a novel RING finger protein that interacts with mad members of the Myc oncoprotein network

Yin, Xiao-Ying, Gupta, Kalpana, Han, Wei Ping, Levitan, Edwin S, Prochownik, Edward V

Journal:

Year:

1999

Language:

english

File:

PDF, 732 KB

english, 1999

32

Lack of transcriptional repression by max homodimers

Yin, Xiaoying, Grove, Linette, Prochownik, Edward V

Journal:

Year:

1998

Language:

english

File:

PDF, 1020 KB

english, 1998

33

The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor development

Zhang, Qiang, Li, Xu, Cui, Kasa, Liu, Cheng, Wu, Mingzhi, Prochownik, Edward V., Li, Youjun

Journal:

Cell Death & Differentiation

Year:

2019

Language:

english

File:

PDF, 3.97 MB

english, 2019

34

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc–Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

Jianxia Guo, Robert A. Parise, Erin Joseph, Merrill J. Egorin, John S. Lazo, Edward V. Prochownik, Julie L. Eiseman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 585 KB

english, 2009

35

Potent Inhibitors Of c-Myc-Max Dimerization Through Multivalent Binding To The Intrinsically Disordered c-Myc Monomer

Follis, Ariele Viacava, Hammoudeh, Dalia, Wang, Huabo, Prochownik, Edward V., Metallo, Steven J.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

36

c-Myc as a therapeutic target in cancer

Prochownik, Edward V

Journal:

Expert Review of Anticancer Therapy

Year:

2004

Language:

english

File:

PDF, 312 KB

english, 2004

37

MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice

Cheng, Li, Zhu, Yahui, Han, Han, Zhang, Qiang, Cui, Kaisa, Shen, Hongxing, Zhang, Jinxiang, Yan, Jun, Prochownik, Edward, Li, Youjun

Journal:

Cell Death and Disease

Year:

2017

Language:

english

File:

PDF, 2.21 MB

english, 2017

38

Inhibition of hepatocellular carcinoma by metabolic normalization

Wang, Huabo, Lu, Jie, Dolezal, James, Kulkarni, Sucheta, Zhang, Weiqi, Chen, Angel, Gorka, Joanna, Mandel, Jordan A., Prochownik, Edward V., Luque, Raul M.

Journal:

Year:

2019

File:

PDF, 2.84 MB

2019

39

Expression patterns of small numbers of transcripts from functionally-related pathways predict survival in multiple cancers

Mandel, Jordan, Wang, Huabo, Normolle, Daniel P., Chen, Wei, Yan, Qi, Lucas, Peter C., Benos, Panayiotis V., Prochownik, Edward V.

Journal:

Year:

2019

Language:

english

File:

PDF, 14.88 MB

english, 2019

40

Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1

Egler, Rachel A, Fernandes, Elaine, Rothermund, Kristi, Sereika, Susan, de Souza-Pinto, Nadja, Jaruga, Pawel, Dizdaroglu, Miral, Prochownik, Edward V

Journal:

Year:

2005

Language:

english

File:

PDF, 372 KB

english, 2005

41

Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt–Mdm2–p53 pathway

Rogulski, Kenneth, Li, Youjun, Rothermund, Kristi, Pu, Lixia, Watkins, Simon, Yi, Fenghua, Prochownik, Edward V

Journal:

Year:

2005

Language:

english

File:

PDF, 863 KB

english, 2005

42

Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc

Hammoudeh, Dalia I., Follis, Ariele Viacava, Prochownik, Edward V., Metallo, Steven J.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 1.83 MB

english, 2009

43

β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice

Zhang, Weiqi, Meyfeldt, Jennifer, Wang, Huabo, Kulkarni, Sucheta, Lu, Jie, Mandel, Jordan A., Marburger, Brady, Liu, Ying, Gorka, Joanna E., Ranganathan, Sarangarajan, Prochownik, Edward V.

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 8.56 MB

english, 2019

44

Commonly occurring loss and mutation of the MXI1 gene in prostate cancer

Edward V. Prochownik, Linette Eagle Grove, Debra Deubler, Xiao Lin Zhu, Robert A. Stephenson, L. Ralph Rohr, Xiaoying Yin, Arthur R. Brothman

Journal:

Genes, Chromosomes and Cancer

Year:

1998

Language:

english

File:

PDF, 341 KB

english, 1998

45

Endothelial Progenitors Exist within the Kidney and Lung Mesenchyme

Sims-Lucas, Sunder, Schaefer, Caitlin, Bushnell, Daniel, Ho, Jacqueline, Logar, Alison, Prochownik, Edward, Gittes, George, Bates, Carlton M., Singh, Shree Ram

Journal:

Year:

2013

Language:

english

File:

PDF, 3.68 MB

english, 2013

46

Relationship between an enhancer element in the human antithrombin III gene and an immunoglobulin light-chain gene enhancer

Prochownik, Edward V.

Journal:

Year:

1985

File:

PDF, 476 KB

1985

47

Expression and Analysis of COOH-Terminal Deletions of the Human Thrombospondin Molecule

Edward V. Prochownik, Karen O'Rourke and Vishva M. Dixit

Journal:

The Journal of Cell Biology

Year:

1989

Language:

english

File:

PDF, 1.77 MB

english, 1989

48

The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth

Li, Wenjuan, Cui, Kaisa, Prochownik, Edward V, Li, Youjun

Journal:

Cell Death and Disease

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

49

Mitochondrial Structure, Function and Dynamics Are Temporally Controlled by c-Myc

Graves, J. Anthony, Wang, Yudong, Sims-Lucas, Sunder, Cherok, Edward, Rothermund, Kristi, Branca, Maria F., Elster, Jennifer, Beer-Stolz, Donna, Van Houten, Bennett, Vockley, Jerry, Prochownik, Edward

Journal:

Year:

2012

Language:

english

File:

PDF, 833 KB

english, 2012

50

Protooncogenes and Cell Differentiation

Edward V. Prochownik

Journal:

Transfusion Medicine Reviews

Year:

1989

Language:

english

File:

PDF, 1.72 MB

english, 1989

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